Acromegaly Occurring In A Patient With A Pituitary Adenoma, Lymphocytic Hypophysitis, And A Rathke Cleft Cyst

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Rathke Cleft Cyst with a Coexisting Gonadotropin Producing Pituitary Adenoma

Rathke cleft cyst is thought to arise from incomplete obliteration of the lumen of Rathke pouch. The cells of the anterior pituitary lobe, from which pituitary adenomas develop, are also derived from the cells of Rathke pouch. Although Rathke cleft cyst and pituitary adenoma have a shared ancestry, they rarely occur coincidentally. Rathke cleft cysts have been found incidentally in 11% 33% of p...

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Lymphocytic hypophysitis occurring simultaneously with a functioning pituitary adenoma.

Lymphocytic Hypophysitis (LH) is a rare and previously under-recognised disorder, most commonly affecting young females in the post-partum period. It presents clinically with symptoms and signs related to either a pituitary mass or hypopituitarism, frequently mimicking a pituitary adenoma; the diagnosis of LH can only be made histologically with the presence of a dense lymphocytic infiltration ...

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Hypophysitis secondary to a ruptured Rathke cleft cyst.

CASE REPORT Case 1 A 31-year-old female consulted for polydipsia and polyuria ongoing since a few weeks. She reported weight gain over the last eight months and amenorhea with galactorhea for the last four months. Physical examination revealed no abnormalities other than a decreased visual acuity in the left eye already noticed by the patient over the past three months. Biochemical and hematolo...

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Coexisting Rathke Cleft Cyst and Pituitary Adenoma Presenting with Pituitary Apoplexy: Report of Two Cases

The authors report two cases of coexisting Rathke cleft cyst (RCC) and pituitary macroadenoma. Both patients presented at the university hospital with pituitary apoplexy symptoms of sudden-onset headache while undergoing treatment with Coumadin (warfarin). Magnetic resonance imaging was consistent with a pituitary adenoma in one case and RCC in the other. Intraoperative findings and pathologica...

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The Coexistence of an Intrasellar Adenoma, Lymphocytic Hypophysitis, and Primary Pituitary Lymphoma in a Patient with Acromegaly

The concomitant presence of three histopathologically different entities in the pituitary gland is a rare occurrence. Most publications identify at least two distinct pathologies, mainly, a pituitary adenoma coexisting with a second intrasellar lesion. We present a case of a 71-year-old female referred for evaluation and treatment of acromegaly. Questioning revealed she was experiencing facial ...

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ژورنال

عنوان ژورنال: AACE Clinical Case Reports

سال: 2017

ISSN: 2376-0605

DOI: 10.4158/ep161369.cr